This study dives into how 1,25-(OH)D, a potent form of vitamin D, influences hair growth. Through a combination of experiments in live mice, hair follicle organ culture, and detailed cellular investigations, we uncovered that this vitamin enhances hair regeneration.
Specifically, we found that 1,25-(OH)D not only extends the growth phase of hair follicles but also improves the abilities of certain skin cells that are vital for hair growth. This process relies on receptors for vitamin D, highlighting the importance of our body’s biological pathways in managing hair health.
Interestingly, our findings showed that 1,25-(OH)D can also negate some of the negative effects of DHT—a hormone often linked to hair loss. Overall, this suggests that vitamin D3 could be an effective treatment option for those experiencing androgenetic alopecia, or common hair loss.
Read More
9
Vitamin D3 improves hair regrowth
Efficacy of Oral Vitamin D Therapy in Patients Suffering from Diffuse Hair Loss (Telogen Effluvium).
We explored the prevalence of diffuse hair loss, specifically telogen effluvium (TE), and the effectiveness of oral vitamin D therapy in treating this issue among women in southern Punjab, Pakistan. Our study involved 40 adult women who received 200,000 IU of vitamin D every two weeks for three months.
After treatment, we assessed the participants' hair growth condition 15 days following their last dose. We found that the average age of the women was 32.2 years, with the age group of 21-30 exhibiting a higher prevalence of TE than those aged 31-40.
Remarkably, 82.5% of the women experienced significant improvement in hair growth after the treatment. We observed that younger women who do not use sunscreen but often consume milk or milk protein showed particularly notable results. This suggests that vitamin D could be a promising option for those struggling with hair loss due to TE.
Read More
9
Vitamin D3 may aid hair growth
Trichotillomania associated with a 25-hydroxy vitamin D deficiency: A case report.
We observed how vitamin D3 may influence hair loss in individuals suffering from trichotillomania, a condition characterized by the compulsive urge to pull out hair. The study focused on two female patients who were experiencing noticeable hair loss on their scalps, assessed using the Massachusetts General Hospital Hair Pulling Scale.
To promote hair growth, both patients were given dietary supplementation of vitamin D3 at a dose of 1000 IU daily. Over a treatment period of 3 to 4 months, we noted significant improvements in both patients. This was evidenced by a reduction in hair loss linked to their obsessive-compulsive disorder, which corresponded with increases in their serum 25-hydroxyvitamin D levels.
The results suggest there's a potential connection between vitamin D deficiency and trichotillomania, particularly how inadequate vitamin D may exacerbate hair loss in those susceptible to this disorder. Overall, we found support in both experimental and clinical evidence for the role vitamin D may play in hair loss associated with trichotillomania.
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Most Useful Reviews
9
Noticeable effect
9 people found this helpful
Jamil Voronin This is something incredible! I've just started taking these vitamins recently, and the effect is already noticeable! I can say that this is simply miraculous - ideal for those suffering from hair loss, I recommend them for autumn.
Read More
7.5
Health improvement
4 people found this helpful
This high-quality dietary supplement worked for me within days. I purchased it for hair loss and bone pain, as advised by my doctor. I noticed a significant boost in my health unexpectedly; I felt revitalised in the mornings, with improved skin and hair. It’s truly miraculous! I’ve enjoyed it, and I plan to continue taking more.
Read More
9
Hair stopped falling
Excellent! These working vitamins were prescribed by my doctor in March 2018, as my Vitamin D level was severely low. The dosage was 2000 units each morning with Omega-3. After 4.5 months, tests showed a significant increase in Vitamin D levels, and externally, my hair improved significantly—hair loss ceased, and it became much thicker.
This study dives into how 1,25-(OH)D, a potent form of vitamin D, influences hair growth. Through a combination of experiments in live mice, hair follicle organ culture, and detailed cellular investigations, we uncovered that this vitamin enhances hair regeneration.
Specifically, we found that 1,25-(OH)D not only extends the growth phase of hair follicles but also improves the abilities of certain skin cells that are vital for hair growth. This process relies on receptors for vitamin D, highlighting the importance of our body’s biological pathways in managing hair health.
Interestingly, our findings showed that 1,25-(OH)D can also negate some of the negative effects of DHT—a hormone often linked to hair loss. Overall, this suggests that vitamin D3 could be an effective treatment option for those experiencing androgenetic alopecia, or common hair loss.
Read More
9
Vitamin D shows promise for hair loss
Treatment of alopecia totalis/universalis/focalis with vitamin D and analogs: Three case reports and a literature review.
We explored the potential of vitamin D3, particularly its active form calcitriol, in treating various types of hair loss, including alopecia totalis, universalis, and focalis. Our focus was on three young girls who had battled with severe hair loss for extended periods without success in previous treatments.
Over the course of the study, we initiated a regimen that started with a six-month course of vitamin D3 repletion using oral cholecalciferol, which did not yield immediate results. However, upon switching to calcitriol and its analog, paricalcitol, two out of the three girls experienced significant hair regrowth. One girl saw hair begin to regrow within six months, and her progress stabilized over the next four years with increased doses.
The second patient faced some side effects, such as mild hypercalcemia when taking calcitriol, which we successfully managed by transitioning to paricalcitol. Meanwhile, our third patient experienced a rapid resolution of hair loss with a high dose of cholecalciferol. These findings suggest that vitamin D may hold promise as a therapeutic option in managing specific types of alopecia, warranting further study in larger clinical trials.
Read More
9
Vitamin D3 improves hair regrowth
Efficacy of Oral Vitamin D Therapy in Patients Suffering from Diffuse Hair Loss (Telogen Effluvium).
We explored the prevalence of diffuse hair loss, specifically telogen effluvium (TE), and the effectiveness of oral vitamin D therapy in treating this issue among women in southern Punjab, Pakistan. Our study involved 40 adult women who received 200,000 IU of vitamin D every two weeks for three months.
After treatment, we assessed the participants' hair growth condition 15 days following their last dose. We found that the average age of the women was 32.2 years, with the age group of 21-30 exhibiting a higher prevalence of TE than those aged 31-40.
Remarkably, 82.5% of the women experienced significant improvement in hair growth after the treatment. We observed that younger women who do not use sunscreen but often consume milk or milk protein showed particularly notable results. This suggests that vitamin D could be a promising option for those struggling with hair loss due to TE.
Read More
9
Vitamin D3 may aid hair growth
Trichotillomania associated with a 25-hydroxy vitamin D deficiency: A case report.
We observed how vitamin D3 may influence hair loss in individuals suffering from trichotillomania, a condition characterized by the compulsive urge to pull out hair. The study focused on two female patients who were experiencing noticeable hair loss on their scalps, assessed using the Massachusetts General Hospital Hair Pulling Scale.
To promote hair growth, both patients were given dietary supplementation of vitamin D3 at a dose of 1000 IU daily. Over a treatment period of 3 to 4 months, we noted significant improvements in both patients. This was evidenced by a reduction in hair loss linked to their obsessive-compulsive disorder, which corresponded with increases in their serum 25-hydroxyvitamin D levels.
The results suggest there's a potential connection between vitamin D deficiency and trichotillomania, particularly how inadequate vitamin D may exacerbate hair loss in those susceptible to this disorder. Overall, we found support in both experimental and clinical evidence for the role vitamin D may play in hair loss associated with trichotillomania.
Read More
8
Microneedling with Vitamin D3 is effective
Combined microneedling with topical vitamin D3 or bimatoprost versus microneedling alone in the treatment of alopecia areata: A comparative randomized trial.
We explored the effectiveness of vitamin D3 in treating alopecia areata (AA), a condition that leads to hair loss. To do this, we conducted a study with 75 participants, dividing them into three groups. One group received microneedling treatment alone, while the other two groups received microneedling combined with either topical vitamin D3 or bimatoprost, a drug known to promote hair growth.
Throughout the study, we measured participants' progress using clinical evaluations and a scoring system to gauge hair regrowth. Interestingly, both the vitamin D3 and bimatoprost groups showed significant improvements in hair regrowth compared to the microneedling-only group. However, after three months, we found no notable difference between the regrowth achieved with vitamin D3 and that with bimatoprost.
Importantly, all treatments were well tolerated, with only mild and temporary side effects reported. This leads us to conclude that while vitamin D3 in combination with microneedling offers a promising approach for localized AA, its benefits may not be significantly greater than those of bimatoprost.
Jamil Voronin This is something incredible! I've just started taking these vitamins recently, and the effect is already noticeable! I can say that this is simply miraculous - ideal for those suffering from hair loss, I recommend them for autumn.
Read More
7.5
Health improvement
4 people found this helpful
This high-quality dietary supplement worked for me within days. I purchased it for hair loss and bone pain, as advised by my doctor. I noticed a significant boost in my health unexpectedly; I felt revitalised in the mornings, with improved skin and hair. It’s truly miraculous! I’ve enjoyed it, and I plan to continue taking more.
Read More
9
Hair stopped falling
Excellent! These working vitamins were prescribed by my doctor in March 2018, as my Vitamin D level was severely low. The dosage was 2000 units each morning with Omega-3. After 4.5 months, tests showed a significant increase in Vitamin D levels, and externally, my hair improved significantly—hair loss ceased, and it became much thicker.
Read More
9
Less worry
Fine! I ordered these vitamins for my 15-year-old daughter. The issues with hair loss have disappeared, making her less anxious about her upcoming exams. She used to tire easily, but now she has more energy and her skin's condition has improved. After researching, this option seemed best for teenagers as they are well absorbed. We are pleased!
Read More
9
Stopped hair loss
Excellent composition! My doctor prescribed Vitamin D3 after I experienced hair loss. After two months of taking it, the hair loss stopped completely. I highly recommend it!
Hair loss, also known as alopecia, is a common condition that affects both men and women, characterized by the thinning or complete loss of hair from the scalp or other areas of the body. It can occur due to various factors, including genetics, hormonal changes, medical conditions, and environmental factors. The most prevalent type of hair loss is androgenetic alopecia, often referred to as male or female pattern baldness, which typically results in a receding hairline or thinning crown in men and overall thinning in women.
In addition to genetic predisposition, hair loss can be triggered by stress, poor diet, certain medications, and underlying health issues such as thyroid disorders or autoimmune diseases. There are various treatment options available, ranging from over-the-counter products like minoxidil to prescription medications and hair restoration procedures, depending on the severity and cause of hair loss. It's crucial to consult with a healthcare professional to determine the most appropriate treatment plan tailored to individual needs and conditions.
Vitamin D is a fat-soluble vitamin that's essential for maintaining healthy bones and teeth, supporting immune system function, and facilitating normal cell growth and development. It plays a crucial role in calcium absorption in the gut, which is vital for bone health. Unlike most vitamins, our bodies can produce Vitamin D when exposed to sunlight, specifically UVB rays, which is why it’s often referred to as the "sunshine vitamin." However, depending on your geographical location, lifestyle, and skin type, getting sufficient Vitamin D from the sun alone can be challenging, particularly during the winter months.
In addition to sunlight, Vitamin D can be obtained from certain foods such as fatty fish (like salmon and mackerel), fish liver oils, and fortified foods like milk and cereals. Some individuals may also consider supplements, especially if they're at risk for deficiency. Insufficient vitamin D levels are linked to various health issues, including rickets in children, osteomalacia in adults, and even an increased risk of chronic diseases. Regularly checking your vitamin D levels and consulting with a healthcare professional can help ensure you're meeting your needs for optimal health.
Vitamin D plays a critical role in various bodily functions, including the health of hair follicles. Research has indicated that a deficiency in vitamin D may contribute to hair loss, particularly in conditions such as alopecia areata. Vitamin D receptors are found in hair follicles, suggesting that adequate levels of this vitamin can promote healthy hair growth. Supplementing with vitamin D might help those who are deficient and experiencing hair loss, but it’s essential to combine this with a balanced diet and other hair care practices for the best results.
However, while some studies suggest a link between vitamin D and hair health, evidence is still emerging, and further research is necessary to establish a definitive connection. It's crucial to consult with a healthcare provider before starting any supplementation, as they can assess your individual needs and ensure that you’re not exceeding recommended levels, which can have adverse effects. For those looking to improve hair health, focusing on a holistic approach that includes a proper diet, regular exercise, and possibly, vitamin D supplementation, could be more effective than relying solely on one nutrient.
Based on user reviews, the timeline for seeing results from this supplement for hair loss can vary significantly. Some users report noticing improvements within just a few days of starting the supplement, highlighting its effectiveness as an immediate solution for hair loss and revitalizing overall health Read Review. Others have mentioned that it can take longer, such as around two months, for noticeable changes in hair thickness and a complete halt in hair loss Read Review.
In general, many users indicate that after a month or two of consistent use, improvements can be observed, which might include reduced hair loss and increased hair volume Read Review. However, as individual experiences may vary, it's important to pay attention to your own results and consult with a healthcare provider for personalized advice on the duration and dosage suitable for your needs.
Vitamin D3 has shown promising potential in addressing various forms of hair loss through scientific research. A study investigating vitamin D3 deficiency among 120 patients with diffuse hair loss revealed that a significant 79.17% of these individuals were deficient, linking low levels of this vitamin to different types of hair loss including male and female pattern baldness and telogen effluvium [1]. This indicates that replenishing vitamin D3 could be a viable strategy for individuals struggling with hair loss, particularly those who exhibit deficiencies.
Furthermore, vitamin D3 has demonstrated effectiveness in treating specific conditions like alopecia areata. Research comparing intralesional vitamin D3 injections with a well-known corticosteroid treatment found no significant difference in overall improvement but noted that patients preferred the vitamin D3 option due to fewer side effects [2]. Additionally, studies have explored vitamin D's biophysical role, showing its capability to extend hair follicle growth phases and counteract negative influences from hormones linked to hair loss [3]. These findings collectively support the notion that vitamin D3 not only correlates with hair health but may actively play a role in promoting hair regrowth across various conditions.
Based on user reviews, many individuals have reported positive improvements in their symptoms after using the supplement. Several users noted rapid results, claiming to experience visible changes in their hair health within days or weeks of starting the vitamins. For instance, one reviewer mentioned a miraculous effect that was particularly beneficial for those suffering from hair loss Read Review. Others reported a complete cessation of hair loss after a couple of months, alongside increased hair thickness, contributing to overall revitalization Read Review.
In addition to improvements in hair health, many users also highlighted additional benefits, such as increased energy levels, better skin condition, and reductions in anxiety related to hair loss. For example, a review shared that a teenager experienced enhanced energy and confidence after her hair loss issues were addressed by the vitamins Read Review. Similarly, improvements in mood and reduction of stress were reported by users after supplementing their diets with Vitamin D Read Review. While these anecdotal experiences are encouraging, it's important to remember that individual results can vary.
Based on user reviews, many individuals have reported successful experiences when combining this supplement with other dietary aids, particularly Omega-3. One review specifically highlighted that a doctor recommended a daily intake of 2000 units of Vitamin D along with Omega-3 to address low Vitamin D levels, and after several months, noticeable improvements were seen not just in Vitamin D levels, but also in hair thickness and cessation of hair loss Read Review. It seems that this combination can amplify the effects of the Vitamin D supplement, contributing to a more comprehensive approach to handling hair loss and overall well-being.
Users have also reported positive results while taking this supplement alongside traditional treatments suggested by healthcare providers. For example, one reviewer mentioned that the supplement drastically improved her health, resulting in enhanced skin and hair conditions Read Review. Such feedback suggests that integrating this Vitamin D supplement with other recommended supplements or treatments can lead to better outcomes for those dealing with hair loss.
Based on user reviews, a common dosage mentioned for Vitamin D in treating hair loss is around 2000 units daily. One user noted that this dosage was prescribed by their doctor after testing revealed severely low levels of Vitamin D, leading to significant improvements in hair condition after approximately 4.5 months of consistent use Read Review. Additionally, another reviewer who had low Vitamin D levels reported noticeable improvements in their hair and overall vitality after a month of supplementation, although a specific dosage was not provided Read Review.
Overall, users report that Vitamin D supplementation has effectively alleviated their hair loss issues, with many citing improvements in energy levels and overall health. These anecdotal accounts highlight the potential benefits of optimizing Vitamin D levels, but users are encouraged to consult with their healthcare providers to determine the right dosage tailored to their specific needs. Confidence in the results varied, yet many emphasized the importance of testing and monitoring levels for effective treatment Read Review.
7.5
Health improvement
4 people found this helpful
This high-quality dietary supplement worked for me within days. I purchased it for hair loss and bone pain, as advised by my doctor. I noticed a significant boost in my health unexpectedly; I felt revitalised in the mornings, with improved skin and hair. It’s truly miraculous! I’ve enjoyed it, and I plan to continue taking more.
9
Stopped hair loss
Excellent composition! My doctor prescribed Vitamin D3 after I experienced hair loss. After two months of taking it, the hair loss stopped completely. I highly recommend it!
7.5
Improved condition
Vit D I often complained about stress, low mood, and hair loss. After finding out that my Vitamin D level was alarmingly low at 19, I noticed definite improvement after a month of taking it. Get tested and take care of yourself. 🤞
9
Noticeable effect
9 people found this helpful
Jamil Voronin This is something incredible! I've just started taking these vitamins recently, and the effect is already noticeable! I can say that this is simply miraculous - ideal for those suffering from hair loss, I recommend them for autumn.
9
Less worry
Fine! I ordered these vitamins for my 15-year-old daughter. The issues with hair loss have disappeared, making her less anxious about her upcoming exams. She used to tire easily, but now she has more energy and her skin's condition has improved. After researching, this option seemed best for teenagers as they are well absorbed. We are pleased!
9
Hair stopped falling
Excellent! These working vitamins were prescribed by my doctor in March 2018, as my Vitamin D level was severely low. The dosage was 2000 units each morning with Omega-3. After 4.5 months, tests showed a significant increase in Vitamin D levels, and externally, my hair improved significantly—hair loss ceased, and it became much thicker.
7
Vitamin D3 linked to hair loss
Filling the Gaps: Vitamin D Status in Diffuse Hair Fall Among Pakistanis.
We explored the relationship between vitamin D3 levels and diffuse hair loss among a sample of 120 patients in a dermatology clinic. Participants, both male and female, reported losing over 100 strands of hair daily and observed positive results from a hair pull test.
Through our analysis, we found that a staggering 79.17% of these individuals were vitamin D3 deficient. The average vitamin D3 level among the patients was just 17.33 ng/ml. Most of the patients were under 30 years old, indicating that this issue may affect younger adults significantly.
Interestingly, vitamin D3 deficiency was particularly noted in various types of hair loss, including female and male pattern hair loss, diffuse alopecia areata, and telogen effluvium.
This study emphasizes the importance of recognizing and treating vitamin D3 deficiency, especially in patients experiencing diffuse hair fall. By addressing these nutritional gaps, we may offer a viable pathway to help reduce hair loss in affected individuals.
7
Assessing vitamin D3 for hair loss
Intralesional vitamin D3 versus intralesional triamcinolone acetonoid in patchy alopecia areata: a comparative clinical and dermoscopic study.
We explored the effectiveness of intralesional vitamin D3 as a treatment for patchy alopecia areata (AA). This study involved 40 adult participants divided into two groups: one group received vitamin D3 injections, while the other received triamcinolone acetonide injections, both administered every four weeks for up to three sessions.
Our observations included clinical and trichoscopic evaluations at the start of treatment, after each injection, and three months following the treatment sessions. While both treatments showed a significant reduction in AA-specific trichoscopic signs, there was no statistically significant difference in the overall improvement between the two groups.
Interestingly, while both treatments were similarly effective, patients reported fewer adverse effects and greater satisfaction with the vitamin D3 injections. This points to the potential of vitamin D3 as a simpler, safer, and cost-effective option for patients dealing with patchy hair loss. Overall, our findings suggest that intralesional vitamin D3 could indeed be a promising alternative in treating alopecia areata.
9
Vitamin D3 promotes hair growth
1,25-(OH)D promotes hair growth by inhibiting NLRP3/IL-1β and HIF-1α/IL-1β signaling pathways.
This study dives into how 1,25-(OH)D, a potent form of vitamin D, influences hair growth. Through a combination of experiments in live mice, hair follicle organ culture, and detailed cellular investigations, we uncovered that this vitamin enhances hair regeneration.
Specifically, we found that 1,25-(OH)D not only extends the growth phase of hair follicles but also improves the abilities of certain skin cells that are vital for hair growth. This process relies on receptors for vitamin D, highlighting the importance of our body’s biological pathways in managing hair health.
Interestingly, our findings showed that 1,25-(OH)D can also negate some of the negative effects of DHT—a hormone often linked to hair loss. Overall, this suggests that vitamin D3 could be an effective treatment option for those experiencing androgenetic alopecia, or common hair loss.
References
Jalil P, Masood S, Sadique M, Jalil MA, Jalil M, et al. Filling the Gaps: Vitamin D Status in Diffuse Hair Fall Among Pakistanis. Dermatol Pract Concept. 2024;14. doi:10.5826/dpc.1404a232
Ragaie MH, Mohammed SE, Shehata SS. Intralesional vitamin D3 versus intralesional triamcinolone acetonoid in patchy alopecia areata: a comparative clinical and dermoscopic study. J Cosmet Laser Ther. 2024;26:89. doi:10.1080/14764172.2024.2389275
Zong X, Yang S, Tang Z, Li X, Long D, et al. 1,25-(OH)D promotes hair growth by inhibiting NLRP3/IL-1β and HIF-1α/IL-1β signaling pathways. J Nutr Biochem. 2024;132:109695. doi:10.1016/j.jnutbio.2024.109695
Meguid AMA, Ghazally A, Ahmed AM, Bakr RM. Fractional carbon dioxide laser alone and as an assisted drug delivery for treatment of alopecia areata: a clinical, dermoscopic and immunohistochemical study. Arch Dermatol Res. 2023;315:1675. doi:10.1007/s00403-023-02565-x
Ali MS, Hafiz HSA, Ahmed NA, Galal SA. Combined microneedling with topical vitamin D3 or bimatoprost versus microneedling alone in the treatment of alopecia areata: A comparative randomized trial. J Cosmet Dermatol. 2023;22:1286. doi:10.1111/jocd.15569
Papadimitriou DT, Bothou C, Dermitzaki E, Alexopoulos A, Mastorakos G. Treatment of alopecia totalis/universalis/focalis with vitamin D and analogs: Three case reports and a literature review. World J Clin Pediatr. 2021;10:192. doi:10.5409/wjcp.v10.i6.192
Sattar F, Almas U, Ibrahim NA, Akhtar A, Shazad MK, et al. Efficacy of Oral Vitamin D Therapy in Patients Suffering from Diffuse Hair Loss (Telogen Effluvium). J Nutr Sci Vitaminol (Tokyo). 2021;67:68. doi:10.3177/jnsv.67.68
Titus-Lay E, Eid TJ, Kreys TJ, Chu BXJ, Malhotra A. Trichotillomania associated with a 25-hydroxy vitamin D deficiency: A case report. Ment Health Clin. 2020;10:38. doi:10.9740/mhc.2020.01.038
Nayak K, Garg A, Mithra P, Manjrekar P. Serum Vitamin D Levels and Diffuse Hair Fall among the Student Population in South India: A Case-Control Study. Int J Trichology. 2016;8:160. doi:10.4103/ijt.ijt_57_16
Narang T, Daroach M, Kumaran MS. Efficacy and safety of topical calcipotriol in management of alopecia areata: A pilot study. Dermatol Ther. 2017;30. doi:10.1111/dth.12464